How can I induce hypertension on mice?

October 9th, 2008 | by Pressurized |
lizbelle asked:


Please help me. This is part of my research subject in our school.

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  1. 3 Responses to “How can I induce hypertension on mice?”

  2. By mendy on Oct 14, 2008 | Reply

    inject saline into veins while monitoring BP
    or
    feed high salt diet.

  3. By spreedog133 on Oct 16, 2008 | Reply

    In animal surgery during med school in the 1970s, we used to induce hypertension in dogs by partially clamping the renal arteries to reduce renal blood flow and induce a renal/adrenal response which involves the release of vasopressors to increase blood pressure. BUT that surgery would be truly difficult to perform on mice. You might be able to administer the vasopressors directly - whatever the equivalent is for mice. I’ll bet some true researcher out there has done this.
    ‘ Hope they see this question. Good Luck!
    Added note - I was a med student and had no choice. No, I did not like doing that to dogs. I have three rescue dogs as pets here right now who are treated like royalty.

  4. By perfectmrgreen on Oct 19, 2008 | Reply

    play rap music to theme

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